What is Angioleiomyoma?
Angioleiomyoma is a rare, benign, smooth muscle tumor arising from the tunica media of veins and is seldom diagnosed before surgery. Angioleiomyoma can be found throughout the body but occurs most frequently in the lower extremities [1,2,3,4,5,6]. It commonly arises in the dermis or subcutaneous tissue [2].
What is smooth muscle neoplasm?
Uterine smooth muscle tumors are neoplasms composed of smooth muscle; they range from benign leiomyomas to low-grade and high-grade leiomyosarcomas. Several histologic subtypes exist, including usual (spindled), epithelioid, and myxoid tumors.
What are benign smooth muscle tumors called?
A leiomyoma, also known as a fibroid, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%). They can occur in any organ, but the most common forms occur in the uterus, small bowel, and the esophagus.
What is a vascular leiomyoma?
Vascular leiomyoma is a benign, usually solitary tumor arising from the tunica media of the vein. It can occur anywhere in the body wherever smooth muscle is present. These masses are commonly found in the uterus, urogenital tract and gastrointestinal tract but also less commonly in the extremities.
How is Angioleiomyoma treated?
Angiomyolipoma can be treated by the drug everolimus (Afinitor) that works by blocking the human target of rapamycin (mTOR) protein to affect many processes involved in cell growth. Researchers suggest that even if asymptomatic, angiomyolipoma that grows to 3 cm or more in diameter should be treated.
Is Angioleiomyoma painful?
Angioleiomyomas are benign tumors originating in the vascular smooth muscles. The tumor typically presents as a painful, solitary, small subcutaneous nodule.
What is a cancerous tumor in the smooth muscle tissue of the stomach?
Listen to pronunciation. (LY-oh-MY-oh-sar-KOH-muh) A malignant (cancer) tumor of smooth muscle cells that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.
Are smooth tumors cancerous?
Malignant soft tissue tumors are rare cancerous tumors that appear in soft tissues connecting all of your body’s structures, such as muscles and tendons, blood vessels and lymph vessels.
Is a malignant tumor of smooth muscle?
A malignant (cancer) tumor of smooth muscle cells that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.
What are examples of smooth muscle tumors?
Benign smooth muscle tumors include smooth muscle hamartoma and angioleiomyoma. A specific category of leiomyomas are estrogen-receptor positive ones in women. These are similar to uterine leiomyomas and can occur anywhere in the abdomen and abdominal wall.
What is the most serious complication of angiomyolipoma?
The most common serious complication of renal angiomyolipoma is hemorrhage. Epithelioid angiomyolipoma is a recently recognized variant with malignant potential. Angiomyolipoma and lymphangiomyoma are closely related, and tumors with features of both have occurred.
Are malignant tumors smooth?
Thus, tumors are described as smooth muscle tumors if the cells are differentiating towards smooth muscle. We may infer that in fact the tumor arose from smooth muscle, but this is only an inference. Tumors showing differentiation towards smooth muscle include hamartomas, benign tumors, and malignant tumors.
What percentage of soft tissue tumors are malignant?
Malignant soft tissue tumors are still serious. They must be treated with great caution. Malignant soft tissue tumors are rare, making up only about 1% of all malignant tumors. Only about 6,000 of these tumors occur each year in the United States.
Can angiomyolipoma turn malignant?
Renal angiomyolipomas are usually small, and they rarely become a major problem. But a very small proportion can become malignant (cancerous) or cause serious bleeding. Renal AMLs should be monitored carefully.
Does angiomyolipoma require surgery?
Angiomyolipoma of the Kidney. Angiomyolipoma is a condition in which benign tumors form in your kidney. You may have no symptoms, or you may have anemia, fever, pain or high blood pressure. Tumors that grow may need treatment such as embolization or surgery to reduce the risk of bleeding.