How long can you take Revlimid?
You won’t take the drug on days 22 to 28. Revlimid can be taken for up to 12 cycles. Your doctor will likely prescribe Revlimid with the medication rituximab (Truxima, Rituxan).
How effective is Revlimid in treating multiple myeloma?
Patients who took REVLIMID and dexamethasone continuously had a 75% response rate compared to 73% of patients who took REVLIMID and dexamethasone for only 18 months and 62% of patients who took the combination of melphalan, prednisone, and thalidomide.
What is triple class refractory myeloma?
Triple-class refractory disease — more a research term than a clinical term, according to Alfred Garfall, MD, of the Hospital of the University of Pennsylvania in Philadelphia — describes a patient with multiple myeloma who has disease refractory to all three of the major classes of myeloma treatments: …
Can lenalidomide cure multiple myeloma?
Lenalidomide (Revlimid) is similar to thalidomide. It works well in treating multiple myeloma. The most common side effects of lenalidomide are thrombocytopenia (low platelets) and low white blood cell counts. It can also cause painful nerve damage.
What are the long term effects of Revlimid?
It’s possible that Revlimid can cause long-term side effects. For example, this medication may cause: liver problems, such as liver failure. other types of cancer, such as skin cancer or leukemia.
What is the success rate of Revlimid?
Revlimid was given after recovery from tandem autologous transplants. After consolidation/maintenance with Revlimid, 88% of patients achieved at least a very good partial remission and 53% a complete remission. One-year survival was 92%.
What is the best maintenance drug for multiple myeloma?
Maintenance treatments containing the immunomodulatory therapy Revlimid (lenalidomide) are the best option for patients with multiple myeloma, according to a recent meta-analysis. The study, “Maintenance Treatment and Survival in Patients With Myeloma,” was published in the journal JAMA Oncology.
How do you treat triple class refractory multiple myeloma?
The current approaches to the treatment of triple-class refractory disease are limited and include conventional chemotherapy, salvage autologous stem cell transplantation, and recycling previous regimens, each of which have generally had short-lived efficacy.
What does triple refractory mean?
Penta-refractory is defined as someone who has had 2 IMiDs, 2 PIs, and an anti-CD38. We know that the more therapies you have, the OS shortens. So, if you’re triple-refractory, your median OS is 9.2 months, and if you’re penta-refractory, your median OS is 5.6 months.
Does multiple myeloma ever go away?
Multiple myeloma, also known as Kahler’s disease, is a type of blood cancer. There’s no cure, but treatments can slow its spread and sometimes make symptoms go away. A type of white blood cell called a plasma cell makes antibodies that fight infections in your body.
What is considered relapse in multiple myeloma?
Relapsed or recurrent multiple myeloma is when the cancer comes back after you were in remission.
How many times can you go into remission with myeloma?
In roughly 50% of people, repeating the initial therapy will lead to a second remission. This is especially the case for people whose first remissions lasted for 1 year or longer.
How do you know if multiple myeloma is in remission?
Remission after transplantation — The strict definition of remission requires that there are no signs or symptoms of multiple myeloma and that highly sensitive tests cannot detect any abnormal plasma cells. This type of remission occurs in about 50 to 60 percent of people after autologous transplantation.
What is the best treatment for relapsed multiple myeloma?
The standard treatment of relapsed multiple myeloma has been either lenalidomide-dexamethasone (RD) or bortezomib-dexamethasone (VD) but it is changing rapidly for 2 reasons.