Does taking hydrochlorothiazide cause diabetes?
Hydrochlorothiazide (HCTZ) and chlorthalidone are diuretics used to lower blood pressure but may increase your risk for high blood sugar and diabetes.
What are the symptoms of too much hydrochlorothiazide?
Signs of a hydrochlorothiazide overdose include:
- Nausea.
- Muscle weakness.
- Extreme dry mouth and thirst.
- Dizziness.
- Physical weakness.
Will hydrochlorothiazide affect anti diabetic treatment?
We have documented that HCTZ therapy leads to the development of hepatic steatosis and compromised insulin sensitivity in subjects at high risk for type 2 diabetes. Conversely, treatment with Valsartan did not cause ectopic fat redistribution, and in fact, leads to improved insulin sensitivity.
How much does hydrochlorothiazide increase blood sugar?
A 20% or greater rise in the fasting blood sugar occurred in 11 of 24 patients treated with 50 mg hydrochlorothiazide twice daily for six to ten weeks. The blood sugar decreased when potassium was given in conjunction with the diuretic, but the mean fasting blood sugar remained higher than pretreatment levels.
Do water pills raise blood sugar?
Basically, diuretics can affect glucose levels in the blood because they impair glucose metabolism. When the body cannot break down glucose as it should, the glucose level in the blood rises.
Is 50 mg of hydrochlorothiazide too much?
Adults—At first, 12.5 milligrams (mg) or one capsule once a day. Your doctor may want you to take this alone or together with other blood pressure medicines. Your doctor may increase your dose as needed. However, the dose is usually not more than 50 mg per day.
Can hydrochlorothiazide cause neuropathy?
Nervous system side effects including peripheral neuropathy have been reported. Peripheral neuropathy is related to the dose hydralazine used and is more common in slow acetylators. The neuropathy usually first presents as paresthesias, numbness, and tingling in the extremities.
Can diuretics worsen diabetes?
Prolonged thiazide diuretic therapy can lead to glucose intolerance and may occasionally precipitate diabetes mellitus. Short-term metabolic studies, epidemiologic studies, and a variety of clinical trials suggest a connection between ongoing thiazide diuretic use and the development of type 2 diabetes.
Is water pills good for diabetes?
Diuretics (water pills) work better than newer and more costly medicines in the treatment of high blood pressure and prevention of some forms of heart disease in people with type 2 diabetes, according to results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Can diabetics take water pills?
Should diabetics take water pills?
Summary: Diuretics (water pills) work better than newer and more costly medicines in the treatment of high blood pressure and prevention of some forms of heart disease in people with type 2 diabetes, according to results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Can hydrochlorothiazide cause numbness in feet?
Can I take metFORMIN with hydrochlorothiazide?
hydroCHLOROthiazide metFORMIN Talk to your doctor before using hydroCHLOROthiazide together with metFORMIN. HydroCHLOROthiazide can increase blood sugar levels and interfere with diabetic control. You may need a dose adjustment or more frequent monitoring of your blood sugar to safely use both medications.
How do diuretics affect diabetes?
With the current dosages of thiazide diuretics being used in practice, the negative effect of the small increases in blood glucose levels is overshadowed by the beneficial effects seen in clinical trials using thiazides as part of the multidrug regimen that is required to achieve blood pressure control in most patients …
How much does HCTZ raise blood sugar?
Can diuretics cause diabetes?
Can water pills affect blood sugar?
Diuretics can also cause some metabolic alterations which can prove harmful. Basically, diuretics can affect glucose levels in the blood because they impair glucose metabolism. When the body cannot break down glucose as it should, the glucose level in the blood rises.