What is Pachydrusen?

Pachydrusen are large (typically >125 µm), sub-RPE deposits that are yellow-white in color. Additionally, the deposits are distributed across the posterior pole and are isolated or clustered in small groups. The deposits appear with irregular, complex shapes but have distinct borders.

What are the components of drusen?

Drusen are focal yellow-white deposits of extracellular debris, which consist of complement proteins, esterified and nonesterified cholesterol, apolipoproteins, carbohydrates, and trace elements, above the retinal pigment epithelium (RPE) or between the RPE and Bruch’s membrane.

What is Pseudodrusen?

Abstract. Reticular pseudodrusen (RPD), also known as subretinal drusenoid deposits, represent a morphological change to the retina distinct from other subtypes of drusen by being located above the level of the retinal pigment epithelium.

What is a Schisis?

Retinoschisis occurs when a separation (schisis) develops between the two major layers of the retina, creating a blister-like elevation that can be confused with a true retinal detachment.

What is Pachychoroid pigment Epitheliopathy?

Pachychoroid pigment epitheliopathy falls within a spectrum of diseases associated with choroidal thickening that includes central serous chorioretinopathy and polypoidal choroidal vasculopathy, and it should be suspected in eyes with a characteristic fundus appearance related to choroidal thickening and associated …

What color is drusen?

‌There are two types of retinal drusen: hard and soft. ‌Hard drusen are small, dotted, yellow-colored and abnormal tissue growths. When the drusen is hard, there is a lower risk of losing your vision in the future. Soft drusen look large and raised, are pale yellow or grayish-white colored, and have a dome shape.

What do drusen look like?

Drusen are the defining feature of macular degeneration. These small yellow or white spots on the retina can be detected by an ophthalmologist during a dilated eye exam or with retinal photography. People with more than a few small drusen are said to have early age-related macular degeneration (AMD).

What is Drusenoid?

Drusenoid PED was defined as an elevated mound of large drusen or many confluent drusen with well–defined borders, pale yellow to white color, with a minimum diameter of 360 microns.

What does Vitelliform mean?

(vī-tel’i-fōrm), Relating to or resembling the yolk of an egg.

What is split eye?

: an apparent ability to see out of the opposite corners of the two eyes at the same time : extraordinarily acute peripheral vision.

What is white without pressure?

White without pressure (WWP) describes a finding that your retina doctor may see when examining the peripheral retina. WWP is found in 15-30 percent of the population and is characterized by a discrete whitish-gray area in the far peripheral retina that is bordered by a dark line.

What is Srnvm?

SRNVM is a sight threatening disease that causes degenerative changes in macula involving development of leaking vessels with neovascularization. SRNVM’s have been observed idiopathically in both young and old patients.

What is occult CNVM?

Type 1 (“occult”), when the neovascular membrane is located below the RPE. Type 1 CNV demonstrates occult leakage on fluorescein angiography. Polypoidal choroidal vasculoplathy (PCV) is a subtype of Type 1 CNV that is characterized by the presence of polyp-like aneurysmal dilations of the branching vascular network.

What is Pachychoroid spectrum?

Pachychoroid Spectrum refers to a group of clinical entities that have a common characteristic: a pachychoroid. This term derives from greek παχύ, pachy, thick. It refers to a anatomic choroidal characteristic, in which a thickened choroid is present.

What is macular telangiectasia?

Macular telangiectasia (MacTel) is a disease that affects the macula, causing central vision loss. It’s caused by abnormal blood vessels around the fovea. The fovea is the centre of the macula and is used for detailed central vision.

What is fibrovascular PED?

Clinically, a PED appears as a smooth dome-shaped subretinal elevation on fundoscopy and may be associated with other nAMD findings such as drusen, subretinal fluid, hemorrhage, or overlying RPE hyperplasia. Fibrovascular PED in type 1 CNV appears as an irregular RPE elevation with or without serous exudate.

What is fundus Flavimaculatus?

Fundus flavimaculatus (FFM) is a Stargardt-like condition that is later-onset and slow-progressing. FFM presents with white or yellowish-white pisciform flecks possibly with foveal atrophy. While no treatment is available, studies are investigating novel treatment options.

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