What is thalidomide classified?
Thalidomide is in a class of medications called immunomodulatory agents. It treats multiple myeloma by strengthening the immune system to fight cancer cells.
What is the Iupac name of thalidomide?
(RS)-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dioneThalidomide / IUPAC ID
What is thalidomide chemical structure?
C13H10N2O4Thalidomide / Formula
How many sigma bonds are in thalidomide?
Chemical Structure Description The (-)-Thalidomide molecule contains a total of 31 bond(s) There are 21 non-H bond(s), 10 multiple bond(s), 1 rotatable bond(s), 4 double bond(s), 6 aromatic bond(s), 1 five-membered ring(s), 2 six-membered ring(s), 1 nine-membered ring(s) and 2 imide(s) (-thio).
What is Amelia and phocomelia?
Phocomelia, or amelia, is a rare condition that causes very short limbs. It’s a type of congenital disorder. This means it’s present at birth. Phocomelia can vary in type and severity. The condition might affect one limb, the upper or lower limbs, or all four limbs.
What does procure mean in law?
‘see’ to it
The term “procure”, like that of “ensure” or “secure”, imposes a strict obligation so that failure to secure the result amounts to a breach. As Peter Smith J said in Nearfield Ltd v Lincoln Nominees Ltd and others: “…the normal meaning of the word ‘procure’ is to ‘see’ to it”.
What is thalidomide used for?
In the 1950s and 1960s, thalidomide was used to treat morning sickness during pregnancy. But it was found to cause disabilities in the babies born to those taking the drug. Now, decades later, thalidomide (Thalomid) is being used to treat a skin condition and cancer.
Is thalidomide a racemic?
Thalidomide exists in two mirror-image forms: it is a racemic mixture of (R)- and (S)-enantiomers. The (R)-enantiomer, shown in the figure, has sedative effects, whereas the (S)-isomer is teratogenic. Under biological conditions, the isomers interconvert, so separating the isomers before use is ineffective.
What is Tetra-Amelia?
Collapse Section. Tetra-amelia syndrome is a very rare disorder characterized by the absence of all four limbs. (“Tetra” is the Greek word for “four,” and “amelia” refers to the failure of an arm or leg to develop before birth.)
Does the word black mean pale?
The word ‘Black’ can be traced back to its proto Indo-European origins through the word ‘blac’ which meant pale, wan, colourless, or albino. ‘Blac’ was incorporated into Old French as Blanc, Italian and Spanish as Blanco, Bianca, Bianco, Bianchi.
What is procurement of an offence?
Procurement is one form of accessory liability in criminal law (see also aid and abet; counsel). In order to be liable as an accessory for having procured an offence, it is necessary that the accessory’s conduct be causally related to the principal’s offence.
Is procure a formal word?
To procure something is to obtain or get it, especially through special means or extra effort. The word is especially used in the context of the formal, official process of purchasing and obtaining materials, supplies, or equipment, particularly in the context of business or government.
What is the trade name for thalidomide?
Thalomid is the trade name for thalidomide. In some cases, health care professionals may use the trade name thalomid when referring to the generic drug name thalidomide.
What is a DES daughter?
DES daughters: Women whose mothers took DES while pregnant with them. This exposed them to DES while they were growing in the womb. DES sons: Men whose mothers took DES while pregnant with them.