What is Diamox IV used for?
This medication is used with other medications to treat high pressure inside the eye due to certain types of glaucoma. Acetazolamide belongs to a class of drugs known as carbonic anhydrase inhibitors. It works by decreasing the production of fluid inside the eye.
Can Diamox be given IV?
Intravenous or intramuscular injection. The direct intravenous route is preferred as intramuscular use is limited by the alkaline pH of the solution. Hypersensitivity to acetazolamide or to any of the excipients listed in section 6.1. DIAMOX injection should not be used in patients hypersensitive to sulphonamides.
How do you administer acetazolamide?
Drug-Induced Edema: Recommended dosage is 250 to 375 mg of acetazolamide once a day for one or two days, alternating with a day of rest.
How quickly does Diamox work?
How long does acetazolamide take to work? The immediate-release pills can work within 1 to 2 hours.
Does Diamox lower blood pressure?
Acetazolamide showed a clear orthostatic effect by significantly decreasing the standing systolic blood pressure (BP), while propranolol, at the doses used, had no obvious reducing effect on BP.
How does Diamox decrease intracranial pressure?
Abstract. Acetazolamide is one of the most widely used drugs for lowering intracranial pressure (ICP) and is believed to reduce cerebrospinal fluid (CSF) secretion via its action on the choroid plexus (CP).
How do you dilute IV Diamox?
Reconstitute with at least 5 mL sterile water to provide a solution containing not more than 100 mg/mL. Reconstituted solution may be refrigerated (2°C to 8°C) for 1 week, however, use within 12 hours is recommended. Further dilute in D5W or NS for I.V. infusion.
Can you reconstitute acetazolamide with normal saline?
Each 500 mg vial containing sterile acetazolamide sodium should be reconstituted with at least 5 mL of Sterile Water for Injection prior to use.
Does Diamox make you sleepy?
This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy.
Does Diamox lower intracranial pressure?
Acetazolamide is one of the most widely used drugs for lowering intracranial pressure (ICP) and is believed to reduce cerebrospinal fluid (CSF) secretion via its action on the choroid plexus (CP).
Can Diamox treat intracranial hypertension?
Lubow and Kuhr, in 1976, reported a series of IIH patients, many of whom were treated successfully with acetazolamide (Diamox®) and weight reduction. An important study was published in 1978 by Gücer and Viernstein. They used intracranial pressure monitoring before and after treatment in four IIH patients.
Can Diamox reduce CSF?
It may reduce CSF and aqueous humor production, but it has many side effects, ranging from paresthesia, fatigue and drowsiness, to metabolic acidosis, hypokalemia and hyponatremia.
What IV drugs need to be diluted?
The following medications require dilution: ranitidine, famotidine, pantoprazole, lorazepam, promethazine. In certain settings, the following drugs require dilution in order to give them IV push: Digoxin Immune FAB, ephedrine, phentolamine, phenylephrine, phenytoin, vitamin K, magnesium sulfate.
How does Diamox make you feel?
This medication can decrease headache, tiredness, nausea, dizziness, and shortness of breath that can occur when you climb quickly to high altitudes (generally above 10,000 feet/3,048 meters). It is particularly useful in situations when you cannot make a slow ascent.
Can acetazolamide cause death?
Acetazolamide FDA Warning Fatalities have occurred, although rarely, due to severe reactions to sulfonamides including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias.
Does Diamox lower BP?
Does Diamox make you lose weight?
4) Diamox also can cause some stomach pain, nausea and loss of appetite. People often lose 10 pounds when they first go on it. It’s best to take it with a meal. The weight-loss effect doesn’t last or it would be sold as a weight-loss drug.
How serious is IIH?
Idiopathic IH is not usually life threatening, but can be a lifelong problem. While many people find their symptoms are relieved with treatment, but the symptoms can come back and can have a significant impact on your life.