What is arsenic trioxide injection?
ARSENIC TRIOXIDE (AR se nik trye OX ide) is a chemotherapy drug. It slows the growth of cancer cells. This medicine is used to treat acute promyelocytic leukemia (APL). This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
Is arsenic trioxide the same as arsenic?
Arsenic trioxide is the generic name for the trade name drug Trisenox®. In some cases, health care professionals may use the trade name Trisenox® when referring to the generic drug name Arsenic Trioxide. Drug type: Arsenic Trioxide is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.
What is arsenic trioxide used for?
Descriptions. Arsenic trioxide injection is used together with another medicine (eg, tretinoin) to treat newly-diagnosed low-risk acute promyelocytic leukemia (APL), a type of leukemia (cancer of the blood cells). It is also used to treat APL in patients who have not responded to other medication regimens.
How is arsenic trioxide administered?
Arsenic trioxide comes as a solution (liquid) to be injected into a vein by a doctor or nurse in a medical office or clinic. Arsenic trioxide is usually injected over 1 to 2 hours, but it may be injected over as long as 4 hours if side effects are experienced during the infusion.
Is arsenic trioxide a chemotherapy?
Arsenic trioxide is a chemotherapy drug and is also called Trisenox or ATO. It is a treatment for a type of acute myeloid leukaemia called acute promyelocytic leukaemia (APL).
What would happen if you injected arsenic?
Pain/redness/swelling at the injection site, nausea, vomiting, diarrhea, stomach/abdominal pain, tiredness, cough, headache, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What is the difference between arsenate and arsenite?
This difference between arsenite and arsenate is attributed to the fact that their dissolved species are negatively charged and neutral, respectively, at circumneutral pH (arsenite as H3AsO3; arsenate as H2AsO4 − or HAsO4 2−).
Is arsenic trioxide poison?
Arsenic trioxide is readily absorbed if ingested or inhaled, but only slowly absorbed through the skin. Toxicity usually results from ingestion. Acute signs and symptoms include nausea, vomiting, diarrhea, gastrointestinal hemorrhage, cerebral edema, tachycardia, dysrhythmias, and hypovolemic shock.
Is arsenic trioxide a poison?
Does arsenic trioxide cause hair loss?
It does not cause hair loss and is not myelosuppressive in patients with APL. Oncology nurses can play a major role in educating patients about this new drug, explaining its clinical benefits and side effects and the precautions that are necessary for its use.
Which is more toxic arsenate or arsenite?
Why? Arsenites (As3+ or trivalent, arsenic trioxide) are 5–10 times more toxic than arsenates (As5+ or pentavalent) due to their higher solubility.
Is arsenic trioxide chemo?
What is the difference between arsenite and arsenate?
What is the difference between arsenic 3 and 5?
In groundwater, arsenic usually occurs in two forms: trivalent arsenic (As+3, or arsenite) or pentavalent arsenic (As+5, or arsenate). Both are harmful to humans, but trivalent arsenic is more harmful and more difficult to remove from water.