What is modified Rodnan skin score?
The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma).
How is modified Rodnan skin score calculated?
The modified Rodnan skin score (MRSS) is a standard outcome measure for skin disease in SSc and calculated by summation of skin thickness in 17 different body sites (total score = 51). Our objective was to evaluate the sensitivity of change over time of individual body sites used in the calculation of total MRSS.
What is skin score?
A semiquantitative measure of cutaneous involvement that improves prediction of prognosis in systemic sclerosis. Arthritis Rheum.
Can you have scleroderma without skin involvement?
It is possible to have systemic sclerosis without skin thickening (sine scleroderma), which is when there are internal organ manifestations without skin findings, but this is very rare.
What is Morphea scleroderma?
Morphea, also known as localized scleroderma, is a condition which causes hardening and discoloration of the skin. It is thought to be isolated to the skin without internal organ involvement as seen in systemic sclerosis (commonly known as scleroderma).
What is the scleroderma skin pinch test?
“In using a skin scoring system, the physician pinches various parts of the patient’s body to test for thickness. The less skin that can be pinched equals a higher score in diagnosing scleroderma,” says Feghali-Bostwick.
How do I check my skin score?
- Download the Best Skincare App. Start by downloading the free YouCam Makeup app, available for both iOS and Android.
- Enter Skin Score. Then, tap the Skin Score tile in the top left of the app.
- Take a Picture.
- Get an Instant Skin Analysis.
- Use Skin Diary to Keep Skin Score Result.
What is the difference between morphea and scleroderma?
Scleroderma is a disease of unknown origin that affects the microvasculature and loose connective tissues of the body and is characterized by fibrosis and obliteration of vessels in the skin, lungs, gut, kidneys and heart. Morphea is a localized form of scleroderma and affects primarily just the skin.
Can morphea be misdiagnosed?
Its clinical findings are diverse, ranging from erythematous to hypopigmented or hyperpigmented patches or plaques1. Due to this variability, morphea may be misdiagnosed especially by non-dermatologists as pigmentary disorders such as vitiligo2.
Is Morphea scleroderma fatal?
Pansclerotic morphea can be localized to relatively small areas of the body or can involve large areas of the body. Severe cases of pansclerotic morphea can produce long-term disability and on rare occasion have resulted in death.
Is morphea serious?
Morphea is a rare skin condition that will usually only affect the appearance of the skin and will go away without treatment. However, in more severe cases, morphea can cause mobility issues or deformities. In children, morphea can cause eye damage and problems with limb growth and movement.
What are the markers for scleroderma?
Typically, the rheumatologist will order an ANA (antinuclear antibody, an antibody commonly found in many of the autoimmune diseases), as well as an Scl-70 antibody (positive in some patients with diffuse scleroderma), anticentromere antibody (generally felt to be a marker for limited scleroderma), and an antibody …
What is the T-zone on your face?
The skin in the T-zone, which includes the forehead, chin and nose, is oilier than other areas. It shines and tends to develop impurities, as the sebaceous glands in this area of the face are especially active. The cheeks, on the other hand, are normal to dry.
What triggers morphea?
Morphea may be triggered by radiation therapy, repeated trauma to your skin, environmental exposure, or an infection. Morphea isn’t contagious, so you can’t get it from or spread it by touching someone else.
What is the best treatment for morphea?
For severe or widespread morphea, your doctor may prescribe an immunosuppressive medication, such as oral methotrexate (Trexall), corticosteroid pills or both. Or your doctor may suggest hydroxychloroquine (Plaquenil) or mycophenolate mofetil. Each of these drugs has potential side effects.
What’s the difference between scleroderma and morphea?
What labs are abnormal with scleroderma?
Blood tests: Elevated levels of immune factors, known as antinuclear antibodies, are found in 95% of patients with scleroderma. Although these antibodies are also present in other autoimmune diseases such as lupus, testing for them in potential scleroderma patients is helpful in assisting with an accurate diagnosis.